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Colts’ Sunday-night trip to Chiefs spotlights Alec Pierce’s status and Indianapolis’ run-defense questions

The Kansas City Chiefs preview lists a prime-time matchup against the Indianapolis Colts on Sunday night, noting Colts receiver Alec Pierce missed Thursday practice with a heel issue and Indianapolis surrendered 202 rushing yards to the Ravens in Week 1. Pierce’s availability and adjustments to stop Kansas City’s rushing attack are key uncertainties.

BUSINESSINDY BRIEFBy BusinessIndy Editorial StaffPublished September 20, 2026 at 1:16 PM EDTLiving story · 2 sources

The Chiefs’ game preview says Kansas City will host the Indianapolis Colts on Sunday night and provides final injury notes: the Chiefs are missing Josh Simmons and Chamarri Conner, while Chris Jones and Mansoor Delane are listed as questionable. For Indianapolis, wide receiver Alec Pierce – who missed Thursday’s practice while managing a heel injury – carries no official designation into the game, making his availability one to watch.

The preview emphasizes two matchup pressures for the Colts: Kansas City’s newly resurgent rushing game (highlighting Ken Walker’s 173-yard performance last week) and the need to contain Colts tailback Jonathan Taylor. The Chiefs note Indianapolis allowed 202 rushing yards to Baltimore in Week 1 and that Colts Defensive Coordinator Lou Anarumo will likely have adjustments to deploy, leaving game-planning and personnel decisions unresolved heading into Sunday night.

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