Lilly reports retatrutide outperformed Ozempic 2 mg in Phase 3 diabetes trial
At 80 weeks, both retatrutide doses lowered A1C by an average of 2.2%, compared with 1.8% for Ozempic 2 mg. Average weight loss was 19.5% with retatrutide 9 mg and 20.9% with retatrutide 12 mg, compared with 9.4% for Ozempic 2 mg. Indianapolis-based Eli Lilly and Company announced positive topline results on Oct. 28, 2026, from TRANSCEND-T2D-2, a Phase 3 trial in 1,298 adults with type 2 diabetes. The report was published by Eli Lilly and Company.

At 80 weeks, both retatrutide doses lowered A1C by an average of 2.2%, compared with 1.8% for Ozempic 2 mg. Average weight loss was 19.5% with retatrutide 9 mg and 20.9% with retatrutide 12 mg, compared with 9.4% for Ozempic 2 mg. Indianapolis-based Eli Lilly and Company announced positive topline results on Oct. 28, 2026, from TRANSCEND-T2D-2, a Phase 3 trial in 1,298 adults with type 2 diabetes. The report was published by Eli Lilly and Company.
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