Colts seek first win at Lucas Oil Stadium in Week 3 as tackling woes, injuries shape game plan

The Colts head into Week 3 winless (0-2) and will host the Houston Texans at Lucas Oil Stadium with kickoff set for 2026-09-27 at 1:00 p.m. The preview notes both teams are 0-2 and that a loss would leave the loser 0-3 and 0-1 in the AFC South. Players and coaches called the game “mandatory” as the team looks for its first victory.

Indiana defensive concerns highlighted in the report include 28 missed tackles (per Pro Football Focus, second-highest in the NFL) and league-worst marks in yards allowed per game, yards per play and points allowed per game. Injuries and roster moves are also in focus: Houston’s Nico Collins missed Week 2 with a hamstring and did not practice Wednesday or Thursday, Colts receivers Alec Pierce (heel) and Ashton Dulin (ankle) are limited, and the Colts signed Darius Slayton earlier in the week with his role for Sunday still to be determined.

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